FAIM2 Antibody

Catalog Number:

36459

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BWQ8
NCBI Gene ID: 23017
Gene Accssion: BC000051/Q9BWQ8

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human Fas apoptotic inhibitory molecule 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FAIM2 protein.

Applications:

IHC

Background:

FAIM2 (Fas apoptotic inhibitory molecule 2), also known as LFG (Protein lifeguard), TMBIM2 (Transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid multipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 results in decreased caspase activation and reduced incidence of programmed cell death.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF