Product Datasheet
FAIM2 Antibody
Catalog Number: 36459
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BWQ8
NCBI Gene ID: 23017
Gene Accssion: BC000051/Q9BWQ8
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human Fas apoptotic inhibitory molecule 2
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- LFG; LFG2; NGP35; NMP35; TMBIM2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FAIM2 protein.
- Background:
- FAIM2 (Fas apoptotic inhibitory molecule 2), also known as LFG (Protein lifeguard), TMBIM2 (Transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid multipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 results in decreased caspase activation and reduced incidence of programmed cell death.?
© Signalway Biotechnology All Rights Reserved.