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Catalog Number: |
36412 |
| other_names: | DEP.8; SDP35; DEPDC1A; DEPDC1-V2 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q5TB30 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein corresponding to residues near the C terminal of human DEP domain containing 1 |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total DEPDC1 protein. |
Applications: |
WB |
Background: |
DEP domain containing 1?is a?protein?in humans that is encoded by the DEPDC1?gene. May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. |
References: |
|
appl_detail: |
Western blotting: 1:200-1:1000 |
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