Product Datasheet
DEPDC1 Antibody
Catalog Number: 36412
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q5TB30
NCBI Gene ID: 55635
Gene Accssion: BC065304/Q5TB30
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human DEP domain containing 1
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- DEP.8; SDP35; DEPDC1A; DEPDC1-V2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total DEPDC1 protein.
- Background:
- DEP domain containing 1?is a?protein?in humans that is encoded by the DEPDC1?gene. May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
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