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CXCR6 Antibody

Catalog Number:

36380
other_names: BONZO; CD186; STRL33; TYMSTR

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O00574
NCBI Gene ID: 10663
Gene Accssion: BC033584

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human chemokine (C-X-C motif) receptor 6

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CXCR6 protein.

Applications:

WB IHC

Background:

?Bonzo (also designated STRL33.3) and BOB (brother of Bonzo; also designated GRP15) are seven-transmembrane, G protein-coupled receptors that are closely related to chemokine receptor family members. In conjunction with CD4, several chemokine receptors are known to serve as receptors for HIV-1 entry into cells. Bonzo and BOB are utilized by simian immunodeficiency virus (SIV), HIV-2 and M-tropic HIV-1 for cell entry. Bonzo and BOB are both expressed in lymphoid tissues, and BOB is also expressed in colon.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

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