Product Datasheet
CXCR6 Antibody
Catalog Number: 36380
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00574
NCBI Gene ID: 10663
Gene Accssion: BC033584
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human chemokine (C-X-C motif) receptor 6
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- BONZO; CD186; STRL33; TYMSTR
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CXCR6 protein.
- Background:
- ?Bonzo (also designated STRL33.3) and BOB (brother of Bonzo; also designated GRP15) are seven-transmembrane, G protein-coupled receptors that are closely related to chemokine receptor family members. In conjunction with CD4, several chemokine receptors are known to serve as receptors for HIV-1 entry into cells. Bonzo and BOB are utilized by simian immunodeficiency virus (SIV), HIV-2 and M-tropic HIV-1 for cell entry. Bonzo and BOB are both expressed in lymphoid tissues, and BOB is also expressed in colon.
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