PLEKHO1 Antibody

Catalog Number:

36356

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q53GL0
NCBI Gene ID: 51177
Gene Accssion: BC010149

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human pleckstrin homology domain containing, family O member 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PLEKHO1 protein.

Applications:

WB IHC

Background:

Pleckstrin homology domain-containing family O member 1?is a?protein?that in humans is encoded by thePLEKHO1?gene. Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:300

Datasheet PDF