Product Datasheet  
PLEKHO1 Antibody  
Catalog Number: 36356  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q53GL0
    NCBI Gene ID: 51177
    Gene Accssion: BC010149
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human pleckstrin homology domain containing, family O member 1
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:100-1:300
  • other_names：  
  • OC120; CKIP-1; RP11-458I7.3
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total PLEKHO1 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Pleckstrin homology domain-containing family O member 1?is a?protein?that in humans is encoded by thePLEKHO1?gene. Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.



 
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