1-832-868-1888
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Catalog Number: |
36354 |
| other_names: | p90; CIP2A |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q8TCG1 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein corresponding to a region derived from internal residues of human KIAA1524 |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total KIAA1524 protein. |
Applications: |
WB |
Background: |
Protein CIP2A?also known as?cancerous inhibitor of PP2A?(CIP2A) is a?protein?that in humans is encoded by the?KIAA1524?gene. Protein phosphatase 2A (PP2A) is a cellular tumor suppressor which inhibits cell proliferation and transformation of normal cells to malignant cancer cells. Inhibition of PP2A activity is a prerequisite for human cell transformation. However, the in vivo mechanisms by which PP2A activity is inhibited in spontaneously transformed human cancer cells have been unclear. |
References: |
|
appl_detail: |
Western blotting: 1:500-1:2000 |
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