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KIAA1524 Antibody

Catalog Number:

36354
other_names: p90; CIP2A

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8TCG1
NCBI Gene ID: 57650
Gene Accssion: BC130564

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human KIAA1524

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KIAA1524 protein.

Applications:

WB

Background:

Protein CIP2A?also known as?cancerous inhibitor of PP2A?(CIP2A) is a?protein?that in humans is encoded by the?KIAA1524?gene. Protein phosphatase 2A (PP2A) is a cellular tumor suppressor which inhibits cell proliferation and transformation of normal cells to malignant cancer cells. Inhibition of PP2A activity is a prerequisite for human cell transformation. However, the in vivo mechanisms by which PP2A activity is inhibited in spontaneously transformed human cancer cells have been unclear.

References:

appl_detail:

Western blotting: 1:500-1:2000

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