Product Datasheet
KIAA1524 Antibody
Catalog Number: 36354
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8TCG1
NCBI Gene ID: 57650
Gene Accssion: BC130564
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human KIAA1524
- appl_detail:
- Western blotting: 1:500-1:2000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KIAA1524 protein.
- Background:
- Protein CIP2A?also known as?cancerous inhibitor of PP2A?(CIP2A) is a?protein?that in humans is encoded by the?KIAA1524?gene. Protein phosphatase 2A (PP2A) is a cellular tumor suppressor which inhibits cell proliferation and transformation of normal cells to malignant cancer cells. Inhibition of PP2A activity is a prerequisite for human cell transformation. However, the in vivo mechanisms by which PP2A activity is inhibited in spontaneously transformed human cancer cells have been unclear.
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