SLC12A6 Antibody

Catalog Number:

37030

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UHW9
NCBI Gene ID: 9990
Gene Accssion: NP_598408

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Solute carrier family 12 (potassium/chloride transporters), member 6

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC12A6 protein.

Applications:

IHC

Background:

This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF