Product Datasheet  
SLC12A6 Antibody  
Catalog Number: 37030  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9UHW9
    NCBI Gene ID: 9990
    Gene Accssion: NP_598408
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to a region derived from internal residues of human Solute carrier family 12 (potassium/chloride transporters), member 6
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:50-1:200
  • other_names:  
  • KCC3; ACCPN; KCC3A; KCC3B
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total SLC12A6 protein.
  • Applications:  
  • IHC
  • Background:  
  • This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.



 
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