PIKFYV Antibody

Catalog Number:

36194

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y2I7
NCBI Gene ID: 200576
Gene Accssion: BC032389

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human phosphoinositide kinase, FYVE finger containing

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PIKFYV protein.

Applications:

IHC

Background:

Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF