Product Datasheet
PIKFYV Antibody
Catalog Number: 36194
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y2I7
NCBI Gene ID: 200576
Gene Accssion: BC032389
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human phosphoinositide kinase, FYVE finger containing
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- CFD; FAB1; PIP5K; PIP5K3; ZFYVE29
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PIKFYV protein.
- Background:
- Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate.
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