Product Datasheet  
PIKFYV Antibody  
Catalog Number: 36194  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9Y2I7
    NCBI Gene ID: 200576
    Gene Accssion: BC032389
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to residues near the C terminal of human phosphoinositide kinase, FYVE finger containing
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:50-1:200
  • other_names:  
  • CFD; FAB1; PIP5K; PIP5K3; ZFYVE29
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total PIKFYV protein.
  • Applications:  
  • IHC
  • Background:  
  • Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate.



 
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