KLF17 Antibody

Catalog Number:

36181

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q5JT82
NCBI Gene ID: 128209
Gene Accssion: BC049844

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human Kruppel-like factor 17

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KLF17 protein.

Applications:

IHC

Background:

Krueppel-like factor 17?is a?protein?that in humans is encoded by the?KLF17?gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF