Product Datasheet  
KLF17 Antibody  
Catalog Number: 36181  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q5JT82
    NCBI Gene ID: 128209
    Gene Accssion: BC049844
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to residues near the C terminal of human Kruppel-like factor 17
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:25-1:100
  • other_names：  
  • ZNF393; Zfp393; RP4-675G8.1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total KLF17 protein.
  • Applications：  
  • IHC
  • Background：  
  • Krueppel-like factor 17?is a?protein?that in humans is encoded by the?KLF17?gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.



 
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