SPIRE2 Antibody

Catalog Number:

36144

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8WWL2
NCBI Gene ID: 84501
Gene Accssion: BC139732

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human spire-type actin nucleation factor 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SPIRE2 protein.

Applications:

IHC

Background:

SPIRE2, is a 714 amino acid protein belonging to the spire family.? Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF