Product Datasheet  
SPIRE2 Antibody  
Catalog Number: 36144  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q8WWL2
    NCBI Gene ID: 84501
    Gene Accssion: BC139732
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to residues near the C terminal of human spire-type actin nucleation factor 2
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:25-1:100
  • other_names：  
  • Spir-2
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total SPIRE2 protein.
  • Applications：  
  • IHC
  • Background：  
  • SPIRE2, is a 714 amino acid protein belonging to the spire family.? Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.



 
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