DIRAS3 Antibody

Catalog Number:

36135

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95661
NCBI Gene ID: 9077
Gene Accssion: BC005362

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human DIRAS family, GTP-binding RAS-like 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DIRAS3 protein.

Applications:

IHC

Background:

This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF