ANAPC5 Antibody

Catalog Number:

36113

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UJX4
NCBI Gene ID: 51433
Gene Accssion: BC006301

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human anaphase promoting complex subunit 5

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ANAPC5 protein.

Applications:

WB IHC

Background:

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Datasheet PDF