Product Datasheet  
ANAPC5 Antibody  
Catalog Number: 36113  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9UJX4
    NCBI Gene ID: 51433
    Gene Accssion: BC006301
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to residues near the C terminal of human anaphase promoting complex subunit 5
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:50-1:200
  • other_names：  
  • APC5
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total ANAPC5 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.?



 
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