ACE2 Antibody

Catalog Number:

36103

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BYF1
NCBI Gene ID: 59272
Gene Accssion: BC039902

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ACE2 protein.

Applications:

IHC

Background:

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF