Product Datasheet
ACE2 Antibody
Catalog Number: 36103
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BYF1
NCBI Gene ID: 59272
Gene Accssion: BC039902
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ACE2 protein.
- Background:
- The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63
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