AMBRA1 Antibody

Catalog Number:

36091

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9C0C7
NCBI Gene ID: 55626
Gene Accssion: BC045609

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human autophagy/beclin-1 regulator 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AMBRA1 protein.

Applications:

IHC

Background:

Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF