Product Datasheet  
AMBRA1 Antibody  
Catalog Number: 36091  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9C0C7
    NCBI Gene ID: 55626
    Gene Accssion: BC045609
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to a region derived from internal residues of human autophagy/beclin-1 regulator 1
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Immunohistochemistry: 1:50-1:200
  • other_names:  
  • DCAF3; WDR94
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total AMBRA1 protein.
  • Applications:  
  • IHC
  • Background:  
  • Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.



 
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