Product Datasheet
AMBRA1 Antibody
Catalog Number: 36091
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9C0C7
NCBI Gene ID: 55626
Gene Accssion: BC045609
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human autophagy/beclin-1 regulator 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- DCAF3; WDR94
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AMBRA1 protein.
- Background:
- Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.
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