ACVR1C Antibody

Catalog Number:

36028

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8NER5
NCBI Gene ID: 130399
Gene Accssion: BC022530

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human activin A receptor, type IC

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ACVR1C protein.

Applications:

IHC

Background:

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF