Product Datasheet  
ACVR1C Antibody  
Catalog Number: 36028  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q8NER5
    NCBI Gene ID: 130399
    Gene Accssion: BC022530
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human activin A receptor, type IC
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:15-1:50
  • other_names：  
  • ALK7; ACVRLK7
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total ACVR1C protein.
  • Applications：  
  • IHC
  • Background：  
  • ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).



 
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