TSHR Antibody

Catalog Number:

35980

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P16473
NCBI Gene ID: 7253
Gene Accssion: BC009237

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human thyroid stimulating hormone receptor

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TSHR protein.

Applications:

IHC

Background:

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF