Product Datasheet
TSHR Antibody
Catalog Number: 35980
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P16473
NCBI Gene ID: 7253
Gene Accssion: BC009237
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human thyroid stimulating hormone receptor
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- LGR3; CHNG1; hTSHR-I
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TSHR protein.
- Background:
- The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
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