TAX1BP1 Antibody

Catalog Number:

35972

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q86VP1
NCBI Gene ID: 8887
Gene Accssion: BC050358

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human Tax1 (human T-cell leukemia virus type I) binding protein 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TAX1BP1 protein.

Applications:

IHC

Background:

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF