Product Datasheet  
TAX1BP1 Antibody  
Catalog Number: 35972  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q86VP1
    NCBI Gene ID: 8887
    Gene Accssion: BC050358
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human Tax1 (human T-cell leukemia virus type I) binding protein 1
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:100-1:300
  • other_names：  
  • T6BP; TXBP151; CALCOCO3
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total TAX1BP1 protein.
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[



 
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