RETNLB Antibody

Catalog Number:

35905

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BQ08
NCBI Gene ID: 84666
Gene Accssion: BC113502

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human resistin like beta

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RETNLB protein.

Applications:

IHC

Background:

Resistin-like beta?is a?protein?that in humans is encoded by the?RETNLB?gene. An infusion of either resistin or RELMB in rats rapidly induced severe hepatic but not peripheral insulin resistance. Increases in circulating resistin or RELMB levels markedly stimulated hepatic glucose production despite the presence of fixed physiologic insulin levels. This enhanced rate of glucose output was due to increased flux through glucose-6-phosphatase. The results supported the notion that a novel family of fat- and gut-derived circulating proteins modulates hepatic insulin action.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF