Product Datasheet  
RETNLB Antibody  
Catalog Number: 35905  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9BQ08
    NCBI Gene ID: 84666
    Gene Accssion: BC113502
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human resistin like beta
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50-1:200

  • other_names：  
  • XCP2; FIZZ1; FIZZ2; HXCP2; RELMb; RELMbeta; RELM-beta
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total RETNLB protein.
  • Applications：  
  • IHC
  • Background：  

  • Resistin-like beta?is a?protein?that in humans is encoded by the?RETNLB?gene. An infusion of either resistin or RELMB in rats rapidly induced severe hepatic but not peripheral insulin resistance. Increases in circulating resistin or RELMB levels markedly stimulated hepatic glucose production despite the presence of fixed physiologic insulin levels. This enhanced rate of glucose output was due to increased flux through glucose-6-phosphatase. The results supported the notion that a novel family of fat- and gut-derived circulating proteins modulates hepatic insulin action.




 
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