MAP2K5 Antibody

Catalog Number:

35856

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13163
NCBI Gene ID: 5607
Gene Accssion: BC008838

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human mitogen-activated protein kinase kinase 5

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAP2K5 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF