Product Datasheet  
MAP2K5 Antibody  
Catalog Number: 35856  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q13163
    NCBI Gene ID: 5607
    Gene Accssion: BC008838
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to a region derived from internal residues of human mitogen-activated protein kinase kinase 5
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:50-1:200
  • other_names：  
  • MEK5; MAPKK5; PRKMK5; HsT17454
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total MAP2K5 protein.
  • Applications：  
  • IHC
  • Background：  
  • The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.



 
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