OAS2 Antibody

Catalog Number:

35848

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P29728
NCBI Gene ID: 4939
Gene Accssion: BC049215

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human OAS2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total OAS2 protein.

Applications:

WB IHC

Background:

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

References:

appl_detail:

Western blotting: 1:200-1:1000

Immunohistochemistry: 1:50-1:200

Datasheet PDF