Product Datasheet  
OAS2 Antibody  
Catalog Number: 35848  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P29728
    NCBI Gene ID: 4939
    Gene Accssion: BC049215
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein of human OAS2
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Western blotting: 1:200-1:1000

    Immunohistochemistry: 1:50-1:200

  • other_names：  
  • MGC78578; p69 OAS / p71 OAS;p69OAS / p71OAS
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total OAS2 protein.
  • Applications：  
  • WB IHC
  • Background：  

  • This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.




 
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