CHST6 Antibody

Catalog Number:

34535

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9GZX3
NCBI Gene ID: 4166

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human CHST6.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CHST6 protein.

Applications:

IF

Background:

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.

Akama T.O., Nat. Genet. 26:237-241(2000).
Hemmerich S., Glycobiology 11:75-87(2001).
Bartes A., Biochem. Biophys. Res. Commun. 282:928-933(2001).

References:

appl_detail:

Immunofluorescence: 1:100~1:500

Datasheet PDF