Product Datasheet
CHST6 Antibody
Catalog Number: 34535
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9GZX3
NCBI Gene ID: 4166
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human CHST6.
- appl_detail:
Immunofluorescence: 1:100~1:500
- other_names:
- Carbohydrate sulfotransferase 6; EC 2.8.2.-; N-acetylglucosamine 6-O-sulfotransferase 5; GlcNAc6ST-5; Corneal N-acetylglucosamine-6-O-sulfotransferase
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total CHST6 protein.
- Background:
- Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.
Akama T.O., Nat. Genet. 26:237-241(2000).
Hemmerich S., Glycobiology 11:75-87(2001).
Bartes A., Biochem. Biophys. Res. Commun. 282:928-933(2001).
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