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GCNT3 Antibody

Catalog Number:

34483
other_names: Beta-1; 3-galactosyl-O-glycosyl-glycoprotein beta-1; 6-N-acetylglucosaminyltransferase 3; EC 2.4.1.102; EC 2.4.1.150

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: O95395
NCBI Gene ID: 9245

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human GCNT3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GCNT3 protein.

Applications:

IHC IF

Background:

Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.

Ishibashi Y., Glycoconj. J. 22:53-62(2005).
Huang M.-C., Oncogene 25:3267-3276(2006).
Tan S., Am. J. Respir. Cell Mol. Biol. 36:737-745(2007).

References:

appl_detail:


Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

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