Product Datasheet  
GCNT3 Antibody  
Catalog Number: 34483  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot: O95395
    NCBI Gene ID: 9245
  • Form of Antibody:  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthesized peptide derived from internal of human GCNT3.
  • reactivity:  
  • Hu
  • appl_detail:  

  • Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names:  
  • Beta-1; 3-galactosyl-O-glycosyl-glycoprotein beta-1; 6-N-acetylglucosaminyltransferase 3; EC 2.4.1.102; EC 2.4.1.150
  • Purification:  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity:  
  • The antibody detects endogenous levels of total GCNT3 protein.
  • Applications:  
  • IHC IF
  • Background:  
  • Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.

    Ishibashi Y., Glycoconj. J. 22:53-62(2005).
    Huang M.-C., Oncogene 25:3267-3276(2006).
    Tan S., Am. J. Respir. Cell Mol. Biol. 36:737-745(2007).




 
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