PCNA Antibody

Catalog Number:

31002

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P63261
Gene ID:71

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 9-252 amino acids of Human Proliferating cell nuclear antigen

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total PCNA protein.

Applications:

ELISA WB IHC

Background:

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome

References:

appl_detail:

Predicted MW: 29kd
ELISA: 1:500-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF