Product Datasheet  
PCNA Antibody  
Catalog Number: 31002  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P63261
    Gene ID:71
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Immunogen：  
  • Fusion protein corresponding to a region derived from 9-252 amino acids of Human Proliferating cell nuclear antigen
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 29kd
    ELISA: 1:500-1:5000
    Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:25-1:100

  • other_names：  
  • Proliferating cell nuclear antigen
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total PCNA protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome




 
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