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MRM3 Polyclonal Antibody

Catalog Number:

30613
other_names: MRM3; RMTL1; RNMTL1; mitochondrial rRNA methyltransferase 3

Amount:

100μg
calculated_mw: 47kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9HC36
NCBI Gene ID:55178

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human MRM3 (NP_060616.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

WB 1:500 - 1:2000

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