Product Datasheet
MRM3 Polyclonal Antibody
Catalog Number: 30613
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9HC36
NCBI Gene ID:55178
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human MRM3 (NP_060616.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- MRM3; RMTL1; RNMTL1; mitochondrial rRNA methyltransferase 3
- Purification:
- Affinity purification
- Background:
- Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.
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