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SRSF2 Polyclonal Antibody

Catalog Number:

30475
other_names: SRSF2; PR264; SC-35; SC35; SFRS2; SFRS2A; SRp30b; serine/arginine-rich splicing factor 2

Amount:

100μg
calculated_mw: 28kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q01130
NCBI Gene ID:6427

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human SRSF2 (NP_003007.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11.

References:

appl_detail:

WB 1:500 - 1:2000

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