HAP1 Polyclonal Antibody

Catalog Number:

29811

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P54257
NCBI Gene ID:9001

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human HAP1 (NP_817084.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF