1-832-868-1888
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Catalog Number: |
27532 |
other_names: | PIK3R1; AGM7; GRB1; IMD36; p85; p85-ALPHA; phosphoinositide-3-kinase regulatory subunit 1 |
Amount: |
100μg |
calculated_mw: | 85kDa |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P27986 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human PI3 Kinase p85 alpha (NP_852556.2). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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