IKB alpha Polyclonal Antibody

Catalog Number:

27531

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P25963
NCBI Gene ID:4792

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human IKB alpha (NP_065390.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

References:

appl_detail:

WB 1:500 - 1:2000
IP 1:20 - 1:50

Datasheet PDF