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SQSTM1 / p62 Polyclonal Antibody

Catalog Number:

27522
other_names: SQSTM1; A170; DMRV; FTDALS3; NADGP; OSIL; PDB3; ZIP3; p60; p62; p62B; sequestosome-1

Amount:

100μg
calculated_mw: 62kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q13501
NCBI Gene ID:8878

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human SQSTM1 / p62 (NP_001135770.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF,IP

Background:

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200

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